Leukemia Cutis
Leukemia Cutis Definition: Leukemia cutis (LC) is a rare condition that refers to cutaneous infiltration of neoplastic leukocytes due to peripheral leukemia. Etiology: The etiology of any leukemia can be attributed to genetic and environmental risk factors that promote the expression of neoplastic cells. The proposed etiology of LC involved mechanisms of various chemokines and […]
Leukemia Cutis
Leukemia Cutis Definition: Leukemia cutis (LC) is a rare condition that refers to cutaneous infiltration of neoplastic leukocytes due to peripheral leukemia. Etiology: The etiology of any leukemia can be attributed to genetic and environmental risk factors that promote the expression of neoplastic cells. The proposed etiology of LC involved mechanisms of various chemokines and […]
Lichen Planopilaris
Lichen Planopilaris Definition: Lichen Planopilaris (LP) is an inflammatory primary cicatricial alopecia that can result in permanent hair loss. LP is a follicular variant of lichen planus that results in progressive, patchy and permanent hair loss on the hair-bearing skin surfaces. Etiology: LP is believed to be a hair-specific autoimmune disorder caused by activated T-lymphocytes […]
Lentigo Maligna
Lentigo Maligna Definition: Lentigo maligna (LM), also known as Hutchinson melanotic freckle, is a slow-growing precursor of lentigo maligna melanoma (LMM). LM often occurs in sun-damaged skin of the head and neck region, usually in the elderly. Etiology: LM occurs due to the proliferation of malignant melanocytes within the hair follicle and the basal layer […]
Keloid
Keloid Definition: Keloids are hypertrophic, smooth, hard growths or scars that occur on the skin as a result of excessive scar formation. Keloids may rarely occur spontaneously. They may develop on any part of the body and extend beyond the original wound margins. The upper chest, shoulders, ears and neck are especially prone to keloid […]
Kaposi Sarcoma
Kaposi Sarcoma Definition: Kaposi sarcoma (KS) is a rare disease of the endothelial cells of blood vessels and the lymphatic system. There are four types of Kaposi sarcoma: Classic KS, Human immunodeficiency virus (HIV)- associated KS, endemic or African KS and iatrogenic KS. Etiology: Kaposi sarcoma herpesvirus (KSHV) or Human herpesvirus-8- 8 (HHV-8) is present […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]