Leiomyosarcoma
Leiomyosarcoma Definition: Leiomyosarcoma is an aggressive mesenchymal malignancy and one of the most common subtypes of sarcoma. Leiomyosarcoma typically occurs in the retroperitoneum, uterus and extremities. Etiology: Leiomyosarcoma is a heterogeneous disease primarily associated with RB1 and PTEN tumor suppressor gene mutations. The definitive cause for leiomyosarcoma is unknown, but risk factors have been associated […]
Leiomyosarcoma
Leiomyosarcoma Definition: Leiomyosarcoma is an aggressive mesenchymal malignancy and one of the most common subtypes of sarcoma. Leiomyosarcoma typically occurs in the retroperitoneum, uterus and extremities. Etiology: Leiomyosarcoma is a heterogeneous disease primarily associated with RB1 and PTEN tumor suppressor gene mutations. The definitive cause for leiomyosarcoma is unknown, but risk factors have been associated […]
Keloid
Keloid Definition: Keloids are hypertrophic, smooth, hard growths or scars that occur on the skin as a result of excessive scar formation. Keloids may rarely occur spontaneously. They may develop on any part of the body and extend beyond the original wound margins. The upper chest, shoulders, ears and neck are especially prone to keloid […]
Keloid
Keloid Definition: Keloids are hypertrophic, smooth, hard growths or scars that occur on the skin as a result of excessive scar formation. Keloids may rarely occur spontaneously. They may develop on any part of the body and extend beyond the original wound margins. The upper chest, shoulders, ears and neck are especially prone to keloid […]
Keloid
Keloid Definition: Keloids are hypertrophic, smooth, hard growths or scars that occur on the skin as a result of excessive scar formation. Keloids may rarely occur spontaneously. They may develop on any part of the body and extend beyond the original wound margins. The upper chest, shoulders, ears and neck are especially prone to keloid […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]