Leiomyosarcoma
Leiomyosarcoma Definition: Leiomyosarcoma is an aggressive mesenchymal malignancy and one of the most common subtypes of sarcoma. Leiomyosarcoma typically occurs in the retroperitoneum, uterus and extremities. Etiology: Leiomyosarcoma is a heterogeneous disease primarily associated with RB1 and PTEN tumor suppressor gene mutations. The definitive cause for leiomyosarcoma is unknown, but risk factors have been associated […]
Leiomyosarcoma
Leiomyosarcoma Definition: Leiomyosarcoma is an aggressive mesenchymal malignancy and one of the most common subtypes of sarcoma. Leiomyosarcoma typically occurs in the retroperitoneum, uterus and extremities. Etiology: Leiomyosarcoma is a heterogeneous disease primarily associated with RB1 and PTEN tumor suppressor gene mutations. The definitive cause for leiomyosarcoma is unknown, but risk factors have been associated […]
Keloid
Keloid Definition: Keloids are hypertrophic, smooth, hard growths or scars that occur on the skin as a result of excessive scar formation. Keloids may rarely occur spontaneously. They may develop on any part of the body and extend beyond the original wound margins. The upper chest, shoulders, ears and neck are especially prone to keloid […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bullous Pemphigoid
Bullous Pemphigoid Definition: Bullous Pemphigoid is a chronic autoimmune bullous disease that is characterized by tense bullae on normal or erythematous skin (1). Etiology: Bullous Pemphigoid is caused by autoantibodies against hemidesmosomal proteins BP180 (type XVII collagen) and BP230 that lead to the production of subepidermal blisters (1). Epidemiology: Bullous Pemphigoid is the most common […]
Bites, Arthropod
Bites, ArthropodDefinition: Arthropod bites are skin reactions caused by the bite or sting of different arthropods such as arachnids (spiders,ticks), insects (mosquitoes, fleas, and bedbugs), Chilopods (centipedes) and Diplopods (millipedes)(1). Etiology: The skin reaction is brought on by the entry of venom, saliva, or other compounds from arthropods into the skin, which triggers an inflammatory reaction […]
Impetigo
Impetigo Definition: Impetigo is a common infection of the superficial layers of the epidermis that is very contagious and most often caused by gram-positive bacteria. This condition is characterized by pustules and honey-coloured crusted erosions. It can be classified into non-bullous and bullous impetigo. Etiology: Impetigo is caused by Staphylococcus aureus and less commonly, Streptococcus […]
Granuloma Annulare
Granuloma annulare Condition Name: Granuloma annulare Definition: Granuloma annulare is a benign, chronic skin condition characterized by the formation of annular plaques or papules. Etiology: The exact cause of granuloma annulare is unknown, though it is believed to involve an immune-mediated response. Epidemiology: Granuloma annulare affects individuals of all ages but is more commonly seen […]
Granuloma Annulare
Granuloma annulare Condition Name: Granuloma annulare Definition: Granuloma annulare is a benign, chronic skin condition characterized by the formation of annular plaques or papules. Etiology: The exact cause of granuloma annulare is unknown, though it is believed to involve an immune-mediated response. Epidemiology: Granuloma annulare affects individuals of all ages but is more commonly seen […]