Leiomyosarcoma
Leiomyosarcoma Definition: Leiomyosarcoma is an aggressive mesenchymal malignancy and one of the most common subtypes of sarcoma. Leiomyosarcoma typically occurs in the retroperitoneum, uterus and extremities. Etiology: Leiomyosarcoma is a heterogeneous disease primarily associated with RB1 and PTEN tumor suppressor gene mutations. The definitive cause for leiomyosarcoma is unknown, but risk factors have been associated […]
Leiomyosarcoma
Leiomyosarcoma Definition: Leiomyosarcoma is an aggressive mesenchymal malignancy and one of the most common subtypes of sarcoma. Leiomyosarcoma typically occurs in the retroperitoneum, uterus and extremities. Etiology: Leiomyosarcoma is a heterogeneous disease primarily associated with RB1 and PTEN tumor suppressor gene mutations. The definitive cause for leiomyosarcoma is unknown, but risk factors have been associated […]